Effect of norfloxacin on theophylline metabolism

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Effect of Tinidazole on Norfloxacin Disposition

Background: Concomitant oral administration of NFX with TNZ may affect NFX absorption and consequently its blood concentration and pharmacological effect. Objective: The present study was undertaken to investigate the effect of TNZ on the pharmacokinetics of NFX in healthy volunteers. Methods: This study was conducted as an open-label, randomized, two-way crossover experimental design. After an...

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Effect of Tinidazole on Norfloxacin Disposition

Background: Concomitant oral administration of NFX with TNZ may affect NFX absorption and consequently its blood concentration and pharmacological effect. Objective: The present study was undertaken to investigate the effect of TNZ on the pharmacokinetics of NFX in healthy volunteers. Methods: This study was conducted as an open-label, randomized, two-way crossover experimental design. After an...

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Effect of Tinidazole on Norfloxacin Disposition

Co-administration of norfloxacin (NFX) and tinidazole (TNZ) has been used for the treatment of gastrointestinal and urinary tract infections. Concomitant oral administration of NFX with TNZ may affect NFX absorption and consequently its blood concentration and pharmacological effect. The present study was undertaken to investigate the effect of TNZ at the usual clinical dosage on the pharmacoki...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1989

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.33.2.212